Consider a protein that contains an ER signal sequence at its N-terminus and a nuclear localization sequence in its middle. What do you think the fate of this protein would be? Explain your answer. | Numerade

SOLVED: A nuclear localization signal (NLS) is a sequence of amino acidsthat enables a protein to betransported from the cytoplasm to the nucleus (nuclear import).Import of proteins with a nuclear localization signal into thenucleus requires the nucleotideGTP in the nucleus. How/why is GTP, which does not have NLS, ableto enter into the nucleusfrom the cytoplasm? Make sure your answer addresses keycharacteristics of nuclear transportand describes the process of GTP entry into the nucleus.

Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1

JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols

SOLVED: A new graduate student is asked to add a nuclear localizationsequence (NLS) to the C-terminus of an ER protein in order tolocalize the protein to the nucleus. Which of the followingstatements would be the best response?A. This won't work since the NLS will be cleaved off of theprotein.B. Great idea, but we should remove the ER signal sequence.C. This won't work since the NLS will not be translated.D. Great idea, we can now see if this protein can function inthe nucleus.

Nuclear structure: Video, Causes, & Meaning | Osmosis

Nuclear structure

Lesson 2: Modeling the Nucleus of an Atom | Nuclear Science for Teaching Teens