TGF beta 1 - Wikipedia
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth , cell proliferation , cell differentiation , and apoptosis .
Transforming growth factor beta - Wikipedia
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three [1] different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins.
TGF-β signaling in health, disease and therapeutics
2024年3月22日 · Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular...
TGFB1 gene - MedlinePlus
The TGFB1 gene provides instructions for producing a protein called transforming growth factor beta-1 (TGFβ-1). Learn about this gene and related health conditions.
Transforming Growth Factor Beta Family: Insight into the Role …
The transforming growth factor beta (TGF- β) family forms a group of three isoforms, TGF- β 1, TGF- β 2, and TGF- β 3, with their structure formed by interrelated dimeric polypeptide chains.
TGF-beta signal transduction: biology, function and therapy for ...
2022年12月22日 · The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern in recent years to treat human diseases. This signal controls multiple cellular responses during embryonic development and tissue homeostasis through canonical and/or noncanonical signaling pathways.
Transforming Growth Factor Beta 1 - an overview - ScienceDirect
Transforming growth factor β1 (TGF-β1) is a multifunctional cytokine that plays important roles in cervical neoplasia formation, invasion, progression, and metastasis. TGF-β1 functions as a tumor inhibitor in precancerous lesions and early-stage cancers of cervix whereas as a …
Transforming growth factor-β receptors: versatile mechanisms …
2024年2月13日 · Transforming growth factor-β (TGF-β) signaling is initiated by activation of transmembrane TGF-β receptors (TGFBR), which deploys Smad2/3 transcription factors to control cellular...
A truly transforming growth factor in fibrosis and immunity
2020年5月1日 · TGF-β1 takes center stage in vertebrate embryonic development, in regulating adult tissue homeostasis, and is a key regulator of physiological and pathological tissue repair responses. TGF-β1 is an important cell differentiation, survival, proliferation, and behavior-inducing signalling molecule in all these conditions.
TGF Beta 1 - an overview | ScienceDirect Topics
TGF-beta1 is a multifunctional cytokine produced by various cell types including platelets, lymphocytes, macrophages and mesangial cells. TGF-beta1 is an immunosuppressive cytokine, it inhibits T cell proliferation and the generation of cytotoxic lymphocytes.