Osteopontin shapes immunosuppression in the metastatic niche
2014年9月1日 · The matricellular protein osteopontin (OPN, Spp-1) is widely associated with cancer aggressiveness when produced by tumor cells, but its impact is uncertain when …
Single-cell and spatial analysis reveal interaction of - Nature
2022年4月1日 · We demonstrate that the tumor-specific FAP+ fibroblasts and SPP1+ macrophages were positively correlated in 14 independent CRC cohorts containing 2550 …
The embryonic type of SPP1 transcriptional regulation is re …
Osteopontin (SPP1, a secreted phosphoprotein 1) is primarily involved in immune responses, tissue remodelling and biomineralization. However, it is also overexpressed in many cancers …
The Stromal Processing Peptidase of Chloroplasts is Essential in
2011年8月16日 · Stromal processing peptidase (SPP) is a metalloendopeptidase located in the stroma of chloroplasts, and it is responsible for the cleavage of transit peptides from …
CXCL9:SPP1 macrophage polarity identifies a network of cellular ...
2023年8月3日 · We found that macrophage polarity—defined by CXCL9 and SPP1 (CS) expression but not by conventional M1 and M2 markers—had a noticeably strong prognostic …
Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, …
2022年4月22日 · Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein-1 (SPP1) is a fascinating, multifunctional protein expressed in a number of cell …
The Stromal Processing Peptidase of Chloroplasts is Essential in
Stromal processing peptidase (SPP) is a metalloendopeptidase located in the stroma of chloroplasts, and it is responsible for the cleavage of transit peptides from preproteins upon …
Stromal processing peptidase (SPP) is a metalloendopeptidase located in the stroma of chloroplasts, and it is responsible for the cleavage of transit peptides from preproteins upon …
Identification of Secreted Phosphoprotein 1 (SPP1) as a …
2019年10月1日 · Secreted phosphoprotein 1 (SPP1) is an important extracellular glycoprotein that is associated with immune regulation, tumorigenesis, and cell signaling. However, the …
Secreted phosphoprotein 1 as a potential prognostic and …
2022年1月22日 · Secreted phosphoprotein 1 (SPP1) is involved in immune regulation, cell survival, and tumor progression. Studies have demonstrated that SPP1 plays an important role …