miRNA的功能及其作用机制 - 知乎 - 知乎专栏
很多研究证明 miRNA是通过参与调节其下游基因翻译过程面发挥其生物学功能。 比如，Lai等观察到果蝇miR-2a、miR-2b、miR-6、miR-11、miR-13a及miR-13b等的5'端6~8nt序列具有一定的 …
microRNA - Wikipedia
Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. [2][3] miRNAs base-pair to complementary …
从3分SCI文章分析，miRNA与mRNA相互预测全搞定！ - 知乎
miRNA自从火起来，热度就一直没降过。 本文通过多种在线数据库实例化草掘mPRNA和mRNA，讲解miRNA与mRNA如何相互预测 一 miRNA预测mRNA 1、 Targetscan数据库预测 …
microRNAs in action: biogenesis, function and regulation
2023年6月28日 · miRNAs are RNAs ~22 nucleotides in length that derive from longer primary miRNA (pri-miRNA) transcripts, which bear one or more hairpins (Fig. 1a). Most miRNA …
Overview of MicroRNA Biogenesis, Mechanisms of Actions, …
In this review, we provide an update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations. We also summarize …
MicroRNAs and their targets: recognition, regulation and an
2012年3月13日 · MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways. These small non-coding RNAs bind to target sequences in mRNAs, …
The biogenesis and regulation of animal microRNAs
2024年12月19日 · MicroRNAs (miRNAs) are small, yet profoundly influential, non-coding RNAs that base-pair with mRNAs to induce RNA silencing. Although the basic principles of miRNA …
MicroRNAs: Synthesis, mechanism, function, and recent …
2010年11月1日 · MicroRNAs (miRNAs) are a class of small, endogenous RNAs of 21–25 nucleotides (nts) in length. They play an important regulatory role in animals and plants by …
MicroRNAs: From Mechanism to Organism - Frontiers
2020年6月2日 · Canonical miRNA-silencing mechanism in animals. miRNAs elicit repression of target genes usually through a combination of translational repression and promotion of mRNA …
Origins and Mechanisms of miRNAs and siRNAs - PMC - PubMed …
Two primary categories of these small RNAs— short interfering RNAs (siRNAs) and microRNAs (miRNAs)—act in both somatic and germline line-ages in a broad range of eukaryotic species …