Pleural fluid analysis in adults with a pleural effusion
2024年11月4日 · A systematic approach to analysis of the fluid assists clinicians in narrowing the differential diagnosis or establishing the cause of an effusion.
Macrophages in malignant pleural effusions – alternatively …
Pleural macrophages are involved in local defense mechanisms against environmental pollution, bacteria and cancer. Their main function encompasses phagocytosis of degenerated mesothelial cells. In human pleural effusions macrophages represent more than half of all cells.
Interpreting pleural fluid results - PMC - PubMed Central (PMC)
Pleural fluid (PF) accumulation is a result of disruption in the balance between production and reabsorption. PF is produced primarily by the parietal pleura and reabsorbed via the pleural lymphatics.
Pleural effusion - EMCrit Project
2024年1月10日 · Pleural effusion results from ascitic fluid migrating through defects in the diaphragm into the pleura (similar to hepatic hydrothorax). clinical presentation This generally occurs in postmenopausal women, with a peak incidence around 60 years old.
Hausheer F. Dx & Treatment of malignant pleural effusions. Semin Oncol. 1985;12(1):54-75. Diagnosis? Adenocarcinoma often has large vacuoles with a smooth, well-defined border and a clear interior. Vacuoles may coalesce in adjacent cells.
The panorama of different faces of mesothelial cells - PMC
All effusions in serous cavities represent a pathologic processes secondary to inflammatory, neoplastic, hemodynamic, or mechanical/traumatic etiologies. This elicits reactive changes in the extremely sensitive mesothelial cells lining the serosal surfaces.
Physiology, Pleural Fluid - StatPearls - NCBI Bookshelf
2023年8月28日 · Pleural fluid serves a physiologic function in respiration, while also being a useful measure to diagnose and assess disease, trauma, and other abnormalities. A brief review of the anatomy and physiology of normal pleural fluid gives a point of reference for assessing the causes of abnormal pleural fluid collections and pleural effusions.
Immunologic Characterization of Normal Human Pleural Macrophages ...
2000年3月28日 · In humans, the pleural space is a 20-μm-wide gap between the visceral pleura and the parietal pleura that contains a small volume of fluid. Various cell types occur in the pleural fluid, including macrophages that account for about 50% of free cells ( 1 ).
Getting the most from pleural fluid analysis - SAHN - 2012 ...
2011年11月7日 · The pleural fluid/serum protein ratio is ≤0.50, and the pleural fluid LDH/upper limit of normal serum LDH is ≤0.67. Pleural fluid glucose is equivalent to the serum glucose level, and pleural fluid pH typically ranges from 7.45 to 7.55.
Histiocytic pleural effusion: the strong clue to malignancy
2021年6月16日 · In a previous study on the cellular content of pleural fluid from patients with normal pleura who were undergoing thoracoscopy for hyperhidrosis, approximately 75% of the cells in the pleural fluid were macrophages, belonging to histiocytes . That is, histiocytes comprised a considerable proportion of normal pleural fluid.
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