10-Formyltetrahydrofolate - Wikipedia
10-Formyltetrahydrofolate (10-CHO-THF) is a form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-CHO-THF is used as a substrate in …
10-Formyltetrahydrofolate - an overview | ScienceDirect Topics
Both 5,10-CH 2 -THF and THF can be converted to 10-formyl-THF (10fTHF) required for purine synthesis. 5,10-CH 2 -THF is also reduced to 5-methyl-THF (5mTHF) via the B 2 -dependent …
10-Formyltetrahydrofolate - an overview | ScienceDirect Topics
10-Formyl-THF: Phosphoribosylglycinamide formyltransferase (EC2.1.2.2) and phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase; …
Arabidopsis 10-Formyl Tetrahydrofolate Deformylases Are …
In prokaryotes, PurU (10-formyl tetrahydrofolate [THF] deformylase) metabolizes 10-formyl THF to formate and THF for purine and Gly biosyntheses. The Arabidopsis thaliana genome contains …
Toward a better understanding of folate metabolism in health and ...
10-Formyl-THF. In the absence of antioxidants, 10-formyl-THF is readily oxidized to 10-formyl-DHF (half-life, typically <30 min at 37°C), and on prolonged incubation, is further oxidized to …
Folate metabolism: a re-emerging therapeutic target in ... - Nature
2021年3月11日 · Mitochondrial 10-formyl-THF is used to initiate mitochondrial translation by producing formyl-methionine tRNA. Additionally, as 10-formyl-THF cannot cross the …
Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine ...
2019年10月17日 · ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate metabolism highly expressed in liver, metabolizes 10-formyltetrahydrofolate to produce …
Mechanism of N10-formyltetrahydrofolate synthetase derived from ...
N(10) -formyltetrahydrofolate synthetase (FTHFS) is a folate enzyme that catalyzes the formylation of tetrahydrofolate (THF) in an ATP dependent manner.
THE ENZYMES OF THE 10-FORMYL-TETRAHYDROFOLATE …
In most organisms 10-formyl-tetrahydrofolate (10-CHO-THF) participates in the synthesis of purines in the cytosol and formylation of mitochondrial initiator methionyl-tRNA Met. Here we …
Regulation of folate-mediated one-carbon metabolism by 10 ...
2006年7月7日 · 10-Formyltetrahydrofolate dehydrogenase (FDH) catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to CO(2) and tetrahydrofolate (THF) and is …
- 某些结果已被删除