What Is Cancer? - NCI - National Cancer Institute
Explanations about what cancer is, how cancer cells differ from normal cells, and genetic changes that cause cancer to grow and spread.
Mechanisms of Cancer | Center for Cancer Research
Using recently developed methods of high-throughput analysis, researchers can now study the DNA, RNA and proteins of thousands of individual cells to characterize this heterogeneity and investigate how it affects tumor growth, metastasis and patients’ response to treatment.
Cell Biology of Cancer - SEER Training
A cancer cell is a cell that grows out of control. Unlike normal cells, cancer cells ignore signals to stop dividing, to specialize, or to die and be shed. Growing in an uncontrollable manner and unable to recognize its own natural boundary, the cancer cells may spread to areas of the body where they do not belong.
Fructose Sugar Fuels Cancer Growth Indirectly - NCI
2025年1月14日 · A new study has found that some cancer cells indirectly use fructose to help them grow, relying on the liver to consume fructose and convert it into specific fats, which the cancer cells then take up.
Antibody Removes Abnormal Proteins from Cancer Cells
2023年12月13日 · According to a new study, scientists have designed antibodies that can barge into cancer cells and drag abnormal proteins out, ultimately slowing tumor growth in mice. The approach is a novel way of targeting cancer-fueling proteins that are buried inside cancer cells, several experts said.
A key mechanism that fuels uncontrolled cell growth is ... - Cancer
It was unclear how the TOR protein complex drives the uncontrolled growth of cancer cells. But Grewal and his colleagues discovered that TOR can drive cell division by targeting an RNA processing complex called MTREC (PAXT in humans) that is critical for accurate gene expression and proper chromosome segregation during cell division.
Signals released from dying cancer cells accelerate metastatic …
2023年3月27日 · Cancer cells that die via apoptosis (larger dark purple structures) expel their nuclear contents (orange and yellow stringy structures) to spur metastasis and growth of living cancer cells (smaller light blue structures).
Review: What Is Cancer? - SEER Training
The American Cancer Society defines cancer as "a group of diseases characterized by uncontrollable growth and spread of abnormal cells. If the spread is not controlled, it can result in death." Cancer does not refer to a single disease.
NCI study challenges long-held beliefs about cell division
2023年7月5日 · The finding, led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, and reported July 5, 2023, in Nature, could point toward more effective treatments to interrupt the process by which cancer cells divide quickly and spread.
Cell Metabolism and Cancer | Center for Cancer Research
Cancer cells often abandon the efficient energy-producing pathways used by healthy cells and shift to alternative strategies that generate more of the materials they need to proliferate. Although this shift provides a growth advantage to cancer cells, it also represents a vulnerability.