Reverse-transcriptase inhibitor - Wikipedia
Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase that is required for replication of HIV and other retroviruses.
Reverse Transcriptase Inhibitors - StatPearls - NCBI Bookshelf
2023年6月25日 · Reverse transcriptase inhibitors are medications used in the management and treatment of HIV. It is in the antiretroviral class of drugs. This activity reviews the indication, action, and contraindications for RTIs as a valuable agent in managing HIV (and other disorders when applicable).
Nucleoside reverse transcriptase inhibitors (NRTIs) - Drugs.com
Nucleoside reverse transcriptase inhibitors (NRTIs) are active inhibitors of reverse transcriptase found in retroviruses such as the human immunodeficiency virus (HIV). The different nucleoside reverse transcriptase inhibitors may be activated differently but …
Nucleotide Reverse Transcriptase Inhibitors: A Thorough …
Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment. Toxicol Sci. 2013; 134(2): 323–34. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
Reverse Transcriptase Inhibitors - an overview - ScienceDirect
Reverse Transcriptase Inhibitors are essential components of antiretroviral therapy used in the treatment of HIV. They are categorized into nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs), playing a crucial role in controlling the AIDS epidemic by reducing morbidity and mortality ...
Reverse Transcriptase in HIV: Structure, Function, and Drug …
2025年1月19日 · Reverse transcriptase inhibitors are effective in interrupting the synthesis of viral DNA. These inhibitors are categorized into nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). NRTIs, such as zidovudine and tenofovir, mimic natural nucleotides, halting DNA chain elongation. ...
Lesson 1. Antiretroviral Medications and Initial Therapy - HIV
2024年10月8日 · The HIV reverse transcriptase inhibitors include two classes of antiretroviral medications: nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Emerging Reverse Transcriptase Inhibitors for HIV-1 Infection
There are two distinct types of reverse transcriptase inhibitors, the nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs).
Resistance to reverse transcriptase inhibitors used in the …
Reverse transcriptase inhibitors (RTIs) are routinely used to treat HIV-1 infection. RTIs can also to reduce mother-to-child-transmission of HIV-1 and have been shown to prevent infection in high-risk populations.
Reverse Transcriptase Inhibitors - PubMed
2023年6月25日 · Reverse transcriptase inhibitors are medications used in the management and treatment of HIV. It is in the antiretroviral class of drugs. This activity reviews the indication, action, and contraindications for RTIs as a valuable agent in managing HIV (and other disorders when applicable).