Summary. Alvimopan is a selective µ-opioid receptor antagonist with no central nervous system activity. When orally administered after partial small- or large-bowel resection in patients with ...

Add articles to your saved list and come back to them any time. The state’s top doctor pushed Premier Chris Minns to consider drug responses beyond pill-testing after young people in Sydney ...

In this framework, disruptions in opioidergic signaling due to opioid abuse may mediate social reward processing and behavior. While changes in endogenous opioid peptides and receptors have been ...

Four years ago, the opioid epidemic was brought to the doorstep of Steve’s Music Store when an addictions clinic, Recovery Care, and a specialized pharmacy, Respect RX, opened next door.

The recent discovery that vitamin D induces antimicrobial peptide gene expression explains, in part, the 'antibiotic' effect of vitamin D and has greatly renewed interest in the ability of vitamin ...

Department of Chemistry and Biochemistry, California State University, Los Angeles, California, 90032, United States Department of Chemistry, Hendrix College, Conway, Arkansas 72032, United States ...

People with substance use disorder across the country are not getting a formal say in how most of the approximately $50 billion in opioid lawsuit settlement money is being used to stem the crisis ...

p values <0.05 were considered statistically significant. When Dyn A and PWT2-Dyn A activities were compared in the DMR assay with CHO cells stably expressing the kappa opioid receptor (Figure 5Ci-iii ...

Current research has shown that the administration of opioids results ... and function. The endogenous ligands were found in the mid-1970s and were shown to be peptides (Bradbury et al.