This study addresses fundamental questions surrounding otitis media effusion in Down syndrome, identifying DYRK1A as a key gene involved in the condition. The findings are compelling, highlighting ...

Analogous to smooth muscle cell contraction, phosphorylation of the myosin light chain (MLC) by the Ca 2+ /calmodulin-dependent kinase I, the classic MLC kinase, directs the actin-myosin–based ...

Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) adversely modulates myocyte calcium regulation and is pro-growth and pro-arrhythmic, though targeted drug inhibition is still unavailable.

A creatine kinase test is a blood test that measures levels of an enzyme called creatine kinase. This enzyme supports energy production in the body and is particularly important for muscle and ...

ABSTRACT: Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key regulator of heart function. While some CaMKII activity is beneficial, excessive, or persistent, CaMKII can lead to heart ...

ABSTRACT: Calcium/calmodulin-dependent protein kinase II (CaMKII) is a key regulator of heart function. While some CaMKII activity is beneficial, excessive, or persistent, CaMKII can lead to heart ...

Peggy and Charles Stephenson Cancer Center and Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, United States Peggy and Charles Stephenson Cancer ...

For locally advanced and advanced NSCLC, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-targeted therapy has been the first ... including N-glycans and O-polysaccharides ...

We observed that knocking down Cdk5 in the SCN of mice affects phase delays but not phase advances. This is linked to uncontrolled calcium influx into SCN neurons and an unregulated protein kinase A ...

Moyo Studio / Getty Images Claiming a dependent on your tax return can significantly reduce your tax liability and make you eligible for valuable tax credits. These credits include the child tax ...