Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

The Nobel prizewinner used quantum and molecular mechanics to model the dynamics of complex chemical systems.

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to ...

Protein higher-order structure (HOS) is key to biological function because the mechanisms of protein machinery are encoded in protein three-dimensional structures. Mass spectrometry (MS)-based protein ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, ...

Researchers have innovatively merged protein structural data with genetic sequences to construct evolutionary trees, ...

It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of ...

As the capabilities of generative AI models have grown, you've probably seen how they can transform simple text prompts into hyperrealistic images and even extended video clips.