In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process, which is responsible for the transcription of all protein encoding genes. While the catalytic core of the Pol II ...

Two fundamental mechanisms of gene regulation involve transcription factors and microRNAs, a large class of small, non-coding RNAs. It is widely believed that phenotypic evolution is closely ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

In the case of the trp operon, the ligand tryptophan is required for the repressor to work (repressible negative regulation ... the enzyme required for mRNA transcription. These operator sequences ...

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences ...

An AI foundation model capable of predicting gene activity across many different human cell types may expedite research for ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human ...

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within ...