Cell signaling pathways play a crucial role in various biological processes, including cancer progression and ... and mitogen-activated protein kinase (MAPK) pathways[3]. This finding underscores ...

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK ...

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the ...

a rare cancer with no approved treatments specifically for this disease, and simultaneously progress programs and ...

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

The possibility of a new therapy for colorectal cancer could be achieved by blocking DUSP6, a protein that is important for ...

In particular, I explore pharmacological targeting and characterization of upstream-driven feedbacks of MAPK pathway. I study and characterize the response to KRAS G12C, SOS1 and SHP2 inhibitors alone ...

The study’s lead researcher, Associate Professor Zhang Yongliang from the Department of Microbiology & Immunology at NUS ...

Verastem Oncology (NASDAQ: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced its 2025 priorities and upcoming ...