Raltegravir (Isentress) is an HIV-1 integrase strand-transfer inhibitor with potent antiretroviral activity. It belongs to a class of antiretrovirals called integrase inhibitors. The drug works ...

Dolutegravir is an HIV integrase strand transfer inhibitor ... noninferiority when compared with first-generation HIV INSTI raltegravir. For treatment-experienced patients dolutegravir ...

Caution with concomitant drugs known to cause myopathy or rhabdomyolysis (eg, statins). Isentress HD: concomitant calcium carbonate antacid, rifampin, tipranavir/ritonavir, etravirine: not ...

Lupin has received tentative approval from the Food and Drug Administration for raltegravir tablets, 600 mg, which is a generic of Merck Sharp & Dohme’s Isentress HD tablets. Lupin is the ...

PrEP is another type of medication to help prevent HIV. The main difference between ... alongside 400 mg raltegravir twice a day, or 50 mg dolutegravir once a day. An alternative course is taking ...

Additionally, the emergence of drug resistance in HIV-2 has been a critical area ... could significantly reduce the effectiveness of both raltegravir and dolutegravir[4]. Understanding these ...

[25] Eligible patients had resistance to two or more classes of antiretroviral drugs ... with raltegravir. Dolutegravir also outperformed raltegravir in those patients with HIV viral loads ...