Study in mice and human cadavers hints that a brain-protective gene in the chromosome becomes more active with age.

Human biological sex is determined by the sex chromosomes X and Y. In most cases, females possess two X chromosomes, while males have one X and one Y. However, there is some evidence that the Y ...

The Y chromosome, which determines the sex of human and other mammal babies, is slowly degenerating and may disappear within a few million years, raising fears of extinction. However, a 2022 study ...

The human Y chromosome, responsible for determining male sex, has been gradually shrinking over millions of years. This phenomenon raises intriguing questions about the future of human evolution ...

The Neanderthal Y chromosome is much more closely related to the Y of modern humans than to the Y of Denisovans, another archaic hominin that lived in Eurasia at the same time as Neanderthals, ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair.

A decades-long NIH-backed effort to map the human genome has advanced our understanding of genetic risk factors and human ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair.

A recent Trump executive order defines sex based on gamete size. But the order oversimplifies genetics, hormones and reproductive biology.

As ever, the expression and integrity of the sex-chromosome genes provide a clue. One formerly pseudoautosomal gene, human STS, is only partially X-inactivated, whereas its Y homologue has become ...

When Nettie Steven discovered the Y chromosome in 1905 while studying the mealworm Tenebrio molitor, she identified it as a sex-determining chromosome. As it turns out, the chromosome also has ...