retraction or edge artifacts are not recommended and might be a criteria for sample exclusion for performing or interpreting the HER2 assay. [18] This means that a reliable interpretation of IHC ...

IHC uses a scoring system of 0 to 3 to designate ... Alternate methods of pathologic assessment and interpretation of HER2 testing are being assessed in an effort to improve accuracy.

The analysis was performed on independent study sets of HER2-positive and negative/low breast cancers, already analyzed by central immunohistochemistry (IHC) and FISH testing. Phospho-HER2 and ...