Historically, LPO and iron-catalyzed free radical generation were central to understanding DILI, but the focus shifted toward apoptosis in the late 20th century. The discovery of ferroptosis—a ...

Although it was once thought that most programmed cell deaths occurred by the caspase-dependent program apoptosis, now numerous non-apoptotic programs have been ... with large nutrient stores that ...

Introducing the M@P nanoplatform: a novel approach to cancer therapy that triggers pyroptosis and ferroptosis, boosting ...

Cell biologist Michael Overholtzer explains apoptosis, a form of programmed cell death that can lead to cancer when ... Riegman M, Sagie L, Galed C, Levin T, Steinberg N, Dixon SJ, Wiesner U, ...