On binding to ECM molecules, integrins are thought to undergo a conformational change, which allows the intracellular domain of their β-subunit to interact with focal-adhesion proteins ...

For hydrogels that serve as cell encapsulation platforms, hydrogel degradation must closely match tissue growth. This link is particularly challenging because many of the extracellular matrix (ECM) ...

and although changes in certain other ECM molecules contribute to ECM remodeling, the underlying mechanisms that enable ECM plasticity are still unknown. Synaptic plasticity is a term used to ...

So it is with the extracellular matrix (ECM), the "scaffolding" and "glue" that fill the spaces among cells. New ways of excavating the ECM reveal that it is much more. An eclectic collection of ...

The team specifically focused on the extracellular matrix (ECM), a complex network of molecules that surrounds and supports brain cells. This network plays a critical role in maintaining the ...

These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver, deposition of scar molecules, vascular and organ contraction, and release of cytokines.

Syn-Coll, a synthetic tripeptide derived from the collagen sequence, has garnered attention in scientific research for its hypothesized potential to influence processes associated with extracellular ...