In many species, introduction of double-stranded RNA (dsRNA) induces potent and specific gene silencing, a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in ...

How do cells detect non-self double-stranded DNA (dsDNA) molecules? Several 'sensors' of RNA, including Toll-like ... inhibits the replication of diverse viruses, including the invading pathogen.

A study published in PNAS reveals how a bacterial pathogen coordinates N-acetylneuraminic acid (Neu5Ac) metabolism at the ...

It carries the genetic instructions for the development, functioning, growth, and reproduction of all known organisms and many viruses. DNA is a complex molecule that consists of two strands coiled ...

The innate immune system is your body's first line of defense against harmful invaders like bacteria and viruses ... sensing triggered by self double-stranded RNA following loss of ADAR1 editing ...

A study reveals how Salmonella enterica leverages a small RNA, ManS, to regulate Neu5Ac metabolism and adapt to the host ...

(Illustration: U.S. National Institutes of Health) Adenoviruses are non-enveloped, double-stranded DNA viruses. They can infect both dividing and non ... Lentiviral vectors, derived from HIV-1, are ...