Moore, C. W. et al. DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics 154, 1085–1099 (2000). Myung, K. & Kolodner, R.

A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

DNA is susceptible to damage caused by errors committed during replication and by environmental ... Nicks are potentially deleterious DNA lesions that, if not corrected, may give rise to lethal double ...

Plastic chemicals may harm DNA, as new research reveals how additives disrupt nematode egg formation, suggesting risks to ...

Key TakeawaysBerkeley Lab researchers and their Harvard collaborators examined cell type and brain region specific features ...

Brain cells receive sensory inputs from the outside world and send signals throughout the body telling organs and muscles ...

The following is a summary of “Faulty Gap Filling in Nucleotide Excision Repair Leads to Double-Strand Break Formation in ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

These mechanisms can detect and correct different types of DNA damage, such as base mismatches, single-strand breaks, and double-strand breaks. DNA repair is essential for preventing the accumulation ...

Almost all of these mosaic mutations begin as nucleotide mismatches or damage in only one of the two strands of the DNA prior to becoming double-strand mutations if unrepaired or misrepaired. However, ...