Synta has signed a deal with Roche to develop and commercialize their oral small-molecule inhibitors of calcium-release-activated calcium ... in which the channel mediates antigen-stimulated ...

George is in the GSK graduate program. November, 2014 - Popstdoc Xiaowei Hou is selected among all postdocs in the New York area as a Blavatnik Regional Award Finalist for her pioneering work in the ...

CalciMedica Inc. ("CalciMedica" or the "Company") (Nasdaq: CALC), a clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition ...

To generate the ROS that open the outer membrane calcium channel, the researchers used the dye indocyanine green. This bioactive agent can be activated ... BNN-6, to release nitric oxide molecules ...

There are currently no FDA-approved treatments for FXS, a disease that affects approximately 1 in 4-5000 men and 1 in 6-8000 women globally.

The FDA has granted fast-track designation to an investigational small molecule to treat individuals with Fragile X syndrome, ...